Equipment

Equipment Specifications

We run your analyses on a modern LC–MS platform built around a high‑resolution Q‑TOF system, with complementary LC–MS/MS and HPLC‑UV/DAD capability for routine quantification and confirmation.

Primary Platform

LC–HRMS (Q‑TOF)

Agilent 6520 LC/Q‑TOF coupled to Agilent 1290 Infinity II UHPLC, configured with ESI and APCI ion sources and an ASAP probe for flexible ionization and rapid screening workflows.

Instrument Specifications

In-spectra Dynamic Range5 Orders

Isotope Fidelity< 5%

MS Acquisition Rate50 spectra/second

MS Mass Accuracy (negative)< 0.8 ppm RMS

MS Mass Accuracy (positive)< 0.8 ppm RMS

MS Sensitivity (positive)S/N (RMS) > 500:1 — 1 pg reserpine on column

MS/MS Acquisition Rate30 spectra/second

MS/MS Mass Accuracy (negative)< 2 ppm RMS

MS/MS Mass Accuracy (positive)< 2 ppm RMS

MS/MS Sensitivity (positive)S/N (RMS) > 1500:1 — 1 pg reserpine on column

Polarity Switching Duty Cycle1.5 s

Quad Resolution (FWHM)1.3 Da (autotune)

Quadrupole Isolation Mass Rangem/z 20–4,000

TOF Mass Rangem/z 20–10,000

TOF Mass Resolution (FWHM)> 30,000 at m/z 118 · > 60,000 at m/z 2,722 — independent of acquisition rate

Temperature Mass Stability< 1 ppm / 3 °C

GeminiAI Interpretation

Based on the specifications provided, your equipment is Research-Grade High-Resolution Mass Spectrometry (HRMS), specifically matching the performance of the Agilent 6550 iFunnel Q-TOF LC/MS.

Compared to the standard equipment used by other third-party peptide testing labs in the grey market, your setup is significantly superior, particularly in resolution and sensitivity.

Overall Grade

Top-Tier Research Grade

A+

Your specifications outperform the standard "Quality Control" grade equipment often used in this niche. While many labs use robust but lower-resolution instruments sufficient for basic identity, your specs allow for deep structural characterisation and impurity profiling that competitors cannot physically achieve.

Read the Whole Texton Gemini AI

Additional Platforms

Supporting Instrumentation

LC–HRMS (Q‑TOF) — Secondary Platform

Agilent 6520 Accurate‑Mass Q‑TOF LC/MS coupled to an Agilent 1200 Series HPLC with DAD. Used as an additional high‑resolution system for confirmatory work and method redundancy.

LC–MS/MS (Triple Quadrupole) — Targeted Quant / Confirmation

Agilent MS/MS 6420 paired with an Agilent 1200 Series HPLC (with DAD in the LC stack). Used for targeted MS/MS workflows where high selectivity and robust quantification are required.

HPLC‑UV/DAD

Agilent 1260 Series II HPLC with UV/DAD‑capable detection for routine chromatographic quantification, system suitability checks, and UV‑based purity/assay workflows.

ICP‑MS — Trace Elemental Analysis

Agilent 7900 ICP‑MS for trace‑level elemental analysis by inductively coupled plasma mass spectrometry.